It means to deny that there is a lord of creation who created the entire universe. This is the first of the eleven doctrines above. If it is accepted that “all dhammas arise from hetu-paccaya”, it would be inconsistent to recognize the existence of a separate creator. Every cause is generated by other causes, and every condition is generated by other conditions. Each cause has its own preceding cause, and each condition has its own conditions. Viewed vertically, there is neither beginning nor end, and viewed horizontally, there is neither boundary nor limit. Thus one comes to the conclusion that there is no absolute cause. Believers of the theory of Dependent origination should deny not only the personified creator who gave birth to Brahmins from its mouth, but also the existence of any rationally conceived creator of the cosmos. On the other hand, though believers of Paticcasamuppada deny the existence of any absolute initial cause, they also oppose the point of view that everything is fortuitous. They maintain that no phenomenon emerge without cause, it is subject to inevitable laws—the laws of causation. This is what is meant by “Everything arises from causes”. (From Essentials of Buddhism: Questions and Answers)